Good morning ,
my wife is 35 week pregnant ,and she has itching issue , doctor has suggested uduliv 300 twice a day as her SGOT 32.08 and SGPT 41.47, her thyroid is 5.30. please advise. does it safe to take udilive 300.

Question

Accepted Answer

Itching during pregnancy, especially in the third trimester, can occur for various reasons. Your wife is currently 35 weeks pregnant, and it’s good that her doctor has suggested a treatment for her symptoms. Here's a breakdown of what might be going on:

1. Possible Causes of Itching in Pregnancy:

Cholestasis of Pregnancy: A liver condition that can cause intense itching, particularly on the hands and feet, due to the buildup of bile acids. This condition can sometimes present with abnormal liver function tests, which is why it's important to monitor her liver health.

Hormonal Changes: Pregnancy hormones can also affect skin and bile production, leading to itching, especially as the body adjusts to pregnancy.

Stretch Marks: As the skin stretches, it can become itchy.

Dry Skin: Pregnancy can lead to dehydration or dry skin, causing itching.

2. Understanding the Test Results:

Bilirubin Level (32.08): Elevated bilirubin levels can indicate a liver problem, such as cholestasis. The normal range for bilirubin in pregnancy can vary, but values outside the normal range need attention.

GPT/ALT (1.47): This is an enzyme found in the liver, and the level you’ve mentioned seems to be quite low. The normal range for ALT is typically 7-56 units per liter, so 1.47 could be well within the normal range, indicating no acute liver damage.

3. Udulive 300:

Udulive (Ursodeoxycholic acid) is often used to treat cholestasis of pregnancy and liver conditions. It helps to reduce bile acid levels and improve liver function. The doctor may have prescribed it because it helps with itching associated with liver conditions during pregnancy.

4. What to Watch for:

Intensified Itching: If the itching continues to worsen, especially if it’s concentrated on hands and feet, it’s crucial to monitor for signs of cholestasis of pregnancy.

Jaundice: Watch for yellowing of the skin or eyes, which can be a sign of liver issues.

Fatigue or Abdominal Pain: Any signs of pain in the upper right abdomen or feeling unusually tired could also indicate liver stress.

5. What You Can Do:

Follow the Doctor’s Advice: Continue the prescribed medication as instructed.

Hydration: Ensure she stays hydrated, as dehydration can worsen itching.

Avoid Hot Water Baths: Hot water can exacerbate itching. Instead, use lukewarm water.

Moisturizing: Apply fragrance-free, gentle moisturizers to soothe the skin.

Rest: Encourage her to rest and avoid unnecessary stress.

Conclusion:

The medication Udulive 300 prescribed by your doctor should help with the itching if it is related to a liver condition like cholestasis. It's important to follow up with the doctor regularly and keep an eye on any additional symptoms. If the itching worsens or new symptoms develop, it’s crucial to contact the healthcare provider promptly.

Good morning , my wife is 35 week pregnant ,and she has itching issue , doctor has suggested uduliv 300 twice a day as her SGOT 32.08 and SGPT 41.47, her thyroid is 5.30. please advise. does it safe to take udilive 300.