Amoxicillin Dosage for Children

Amoxicillin Dosage For Children: How to Use, Risks & More

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Amoxicillin is a narrow spectrum Penicillin-based antibiotic that is usually prescribed to treat bacterial infections. Certified by the world health organisation (WHO) as a very safe drug for children, it is usually prescribed for respiratory infections like whooping cough, sinusitis, bronchitis, pneumonia, and throat and middle ear infections. Some skin infections and urinary tract infections (UTIs) are also treated with this antibiotic, based on the culture results.





What Is Amoxicillin?

Amoxicillin is derived from Penicillin, the oldest known antibiotic. It is a better version of its predecessor, the Penicillin, in its ability to tackle a much larger variety of bacterial strains and in its improved ability to get absorbed into the bloodstream. Sold under different brand names, this generic drug called amoxicillin is widely used to treat both gram negative and gram positive bacterial infections occurring in the ear, throat, and upper respiratory system.

Amoxicillin, in combination with potassium clavulanate, is a widely used combination that has enhanced absorption characteristics. The clavulanate additive prevents the formation of the bacterial cell wall, thereby broadening the spectrum of bacteria that can be countered with amoxicillin.




When Do Doctors Prescribe Amoxicillin For Your Kid?

Amoxicillin is an anti-bacterial drug that is used to treat specific strains of bacteria. Contrary to the popular belief among people, this drug does not work against viral infections like flu and the common cold, simply because of its targeted mechanism of action against the bacterial cell wall. Some common infections of the ear, nose and throat (ENT) system are effectively treated with amoxicillin. Here is a list of conditions for which doctors usually prescribe amoxicillin for children.

Child at doctor

  • Acute otitis media, a common type of middle ear infection in children
  • Respiratory infections like sinusitis, bronchitis, pneumonia
  • A whooping cough
  • Throat infections like ‘strep throat’ caused by the streptococcal strain of bacteria
  • Tonsilitis
  • Some skin infections
  • Urinary tract infections

Many mothers tend to self-medicate kids with amoxicillin when the child suffers from these conditions recurrently. It is a very risky and unhealthy practice to administer antibiotics without consulting the doctor, as the dosage and combination may be specific to specific cases. This not only leads to improper treatment but also paves the way the for development of amoxicillin-resistant bacterial strains in the body.





How To Use Amoxicillin?

The generic antibacterial drug called amoxicillin is available under different brand names in the market. It is also available in combination with some chemicals for enhanced action. The child starts getting better usually within two to three days of drug intake. The drug comes in different forms of consumption.

  • Oral suspension: The oral suspension is particularly suitable for children. The antibiotic comes as a powder that can be reconstituted in water or milk. It is usually flavoured to enhance the colour and taste. The cleanliness of the diluting ingredients is essential. Usually, a dosing syringe or a measuring cup is used for accurate dilutions.
  • Paediatric Drops: Paediatric drops are readymade diluted syrups of the desired concentration. It is usually used for small children, where the dosage is very less, and the drug is administered as drops. It comes in a bubble gum flavour.
  • Capsules: Capsules of amoxicillin are also available with varying doses. It is given for slightly grownup children. It is usually taken with water, milk or juice.
  • Regular Tablets: Amoxicillin is also sold as oral tablets that come with immediate release (IR) and extended release (ER). The immediate release tablets come as generic drugs only. The immediate release and the extended-release tablets differ in their respective rate of drug absorption, and the doctor prescribes the preferred version depending upon the patient’s condition.
  • Extended-release Tablets: These tablets are believed to be more effective as they have sustained and elevated doses over long periods.
  • Chewable Tablets: Mildly flavoured chewable tablets are available in the market making it easier for children to consume this drug.

The amoxicillin drug in any of the above forms has to be stored in a cool and dry place away from direct sun and out of reach of children.




Drugs To Avoid Using With Amoxicillin

The treating doctor must be informed about the other drugs that the child is taking. There are many drugs with which amoxicillin has unwanted and adverse reactions, by way of increased or decreased efficacy of the other drug. The ability of the body to collectively excrete the drugs also matters in deciding treatment options. Some of the drugs that should be avoided are:

  • Other anti-bacterial medicines like macrolides, chloramphenicol, tetracycline and sulphonamides
  • Probenecid
  • Allopurinols
  • Warfarin
  • Methotrexate, widely used to treat cancer
  • Live cholera vaccine
  • Venlafaxine

Some children may be taking vitamin supplements or herbal medications for other conditions. Mentioning these drugs to the doctor can be very helpful in avoiding any unwanted reactions, as there is known evidence of an interaction of amoxicillin with vitamins and herbs.





It is also critical to communicate to the doctor about any known history of allergy to amoxicillin or penicillin, before starting the treatment. If the child is suffering from any kidney disease, asthma or hay fever, the doctor has to be informed about it as well, as it will be very critical in deciding the course of treatment.

Amoxicillin Dosage for Kids According to Weight / Age

The dosage of amoxicillin for kids is very different from that of the adults. Typically, the dosage is determined considering parameters like the age of the child, his or her weight, and the degree and nature of the infection. The table below gives a general guideline for determining the dosages.




Infection Age / Weight Moderate Infection Severe Infection
Ear, nose and throat infection Above 3 months and weight <40 Kgs 25 mg/kg per day every 12 hours or 20mg/kg per day every 8 hours 45 mg/kg per day every 12 hours or 40mg/kg per day every 8 hours
Above 3 months and weight >40 Kgs 500mg two times a day or 250mg thrice a day 875mg two times a day or 250mg thrice a day
Lyme disease Weight > 40 kg 500mg to 1g every eight hours for 14 days 500mg to 2 g every eight hours for 10-30 days
Weight < 40 kg 25 to 50mg/kg/day three times a day for 10-21 days 100mg/kg/day three times a day for 10-30 days
Streptococcal Pharyngitis Newborns or babies till 12 weeks age 2 doses of 30mg/kg per day
Age more than 12 weeks 50mg/kg for ten days divided as 2 or 3 doses
Otitis Media (Ear Infection) Age between 4 weeks till 3 months 20-30mg/kg per day after every twelve hours
Age 4 months to 12 years 20-50mg/kg daily after eight to twelve hours 80-90mg/kg per day divided into 2 doses every twelve hours
Tonsillitis or Pharyngitis Age between 4 weeks till 3 months 20-30 mg/kg daily taken every twelve hours
Age 4 months to 12 years 3 doses of 20-50mg/kg per day every eight to twelve hours
Pneumonia Age more than 5 years and weight > 40 kg 500mg to 1g every eight hours
Age between 2 months and 5 years and weight < 40 kg 20 to 90mg/kg/day divided in doses
Urinary tract infection Age > 3 months and weight < 40 kg 25mg/kg/day divided in doses every 12 hours 45mg/kg/day divided in doses every 12 hours
Weight > 40 Kgs 500mg two times a day or 250mg three times a day 875 mg two times a day
Skin or Skin Structure Infection Weight > 40 Kgs 500mg two times a day or 250mg three times a day 875mg two times a day or 250mg thrice a day
Above 3 months and weight >40 Kgs 25 mg/kg per day every 12 hours or 20mg/kg per day every 8 hours 45 mg/kg per day every 12 hours or 40mg/kg per day every 8 hours

A fair idea about the permissible dosage is essential in avoiding any overdose conditions. The numbers mentioned above are a general guide to the drug concentrations. The dosage prescribed by the doctor to the specific cases has to be followed diligently.

mother holds a thermometer

What If You Miss a Dose?

If a dose of amoxicillin is missed, it can be given immediately, provided there is a considerable gap before the next dose. If the time is up for the next dose, then there is no requirement to give a double dosage.





What If Your Child Vomits?

Vomiting is a common side effect of amoxicillin in children. Since the gut microflora is altered by the intake of this drug, it can cause vomiting. Make sure that the kid is taking enough fluids and electrolytes. Usually, consuming food along with the medication helps to control vomiting. Probiotics also help restore the good bacteria in the stomach.

What If You Give an Overdose?

An overdose of the antibiotic may cause intense side effects in children. Depending upon the magnitude of overdose, children experience severe rashes, kidney damage, nausea, and less urination along with many other symptoms. In such cases, immediate medical treatment is mandatory.




How To Treat Overdose?

There is no particular antidote for an amoxicillin overdose in children. To remove the excess amoxicillin from the body, multiple doses of activated charcoal are used. Activated charcoal immediately interrupts the circulation of the antibiotic. Sometimes, doctors wash the stomach to flush out the medicine. Treatment is also given to correct the symptoms arising out of the overdose. Haemodialysis is done for severe cases.

Side Effects of Amoxicillin in Kids

The dosage and frequency of administration vary depending on the severity of the infection and the age of the child. It is advisable to strictly stick to the dosage prescribed by the doctor and finish the full course to avoid development of an antibiotic-resistant strain of the bacteria. Although considered a very safe drug, amoxicillin may cause some mild side effects in children.





  • Stomach discomfort with nausea and mild to severe diarrhoea: This common side effect occurs as a result of changes in the gut flora caused by the antibiotic. If the diarrhoea results in considerable loss of body fluids, it is advisable to consult a medical practitioner immediately.
  • Patches around the mouth, throat and vagina (for girls)
  • Sudden swelling of the throat and tongue coupled with difficulty in breathing: This is categorised as ‘anaphylaxis’ or a severe allergic reaction and requires immediate medical attention
  • Hives or itchy red patches on the skin
  • Loss of appetite
  • Tiredness or weakness after taking a dosage of the drug
  • General fatigue
  • Heavy periods in girls
  • Paleness of the skin
  • Taste aversion
  • Unusual bleeding
  • Burning sensation while urinating

Allergy in kids

Usually, the side effects subside in a day or two as the child’s body gets acclimatised to the drug, but it is better to keep the doctor informed about any new allergic reaction.

Safety Measures While Taking Amoxicillin

While administering amoxicillin, it is better to consult the doctor and get an opinion on the other allowed medications. Vomiting and diarrhoea are common side effects of antibiotic intake. Do not give medication to stop watery stools without consultation with the doctor.




Also, when a child is treated with amoxicillin, the urine sugar levels may show some false positives. In such cases, other methods of measuring the sugar levels can be adopted.

Important Things To Remember About Taking Antibiotics

Some very important things to follow while taking antibiotics are:


  • Strictly follow the dosage and timelines prescribed by the doctor. Increasing or decreasing the dosage can delay the recovery process.
  • Complete the course of antibiotic given for an infection. If the medication is stopped in between, it leads to the development of resistant strains of bacteria.
  • Watch out for any adverse reactions or side effects, especially in children.
  • Avoid any allergic food substances and medicines that have a proven interference with the antibiotic.

Amoxicillin is a safe and effective treatment option for children suffering from various bacterial infections. If your doctor prescribes this drug, keep the above pointers in mind to ensure your child’s quick recovery.

Also Read: 13 Home Remedies for Cold and Flu in Babies